Addiction to legally prescribed pain-relief medication is rife in eastern Tennessee

Trump adviser’s removal from security council seen as orchestrated by HR McMaster

Kerry and Albright join business leaders criticising curbs on some foreigners

Donald Trump’s chief adviser will have unprecedented role on US National Security Council

Security Council postpones vote on resolution calling for halt to settlement building

Cross-border operation – denied by Pakistan – ratchets up tensions between neighbours

Weekend Read: The US president’s historic visit to Cuba this week was a victory lap for his doctrine of diplomacy. But it's one of Obama’s few foreign-policy success stories

Fine Gael is in the driving seat in Leinster House, but its destination remains unclear

Benghazi hearing showcased ‘good’ Hillary, but there were flashes of ‘bad’

House committee to question former secretary of state over deadly 2012 attacks in Libya

Encounter is first with a Cuban leader on US soil in more than six decades

US threatens to support UN sanctions if Salva Kiir backtracks on deal with rebels

US President would be helped along if Netanyahu loses next week’s Israeli elections, as now looks possible

Obama had earlier noted ‘substantial disagreement’ over Iranian nuclear weapons

Political future of Israeli leader at stake in controversial Washington address

More than 40 Democrats boycotting Binyamin Netanyahu speech at US Capitol

Israeli prime minister on mission to tell congress of nuclear-armed Iran

Israeli leader claims abandonment of pledge to prevent Iran from getting a nuclear bomb

Two-year plan’s priorities include avoiding getting stuck in large military operations

Chuck Hagel is first US cabinet member to stand down after midterm election losses