Niall Woods is ruled out of the London Irish side by a hamstring injury. Conor O'Shea, Justin Bishop and Malcolm O'Kelly are all back following their Ireland Test commitments.
Scrum-half Kyran Bracken's back problem has healed after a six-week absence, so the England international takes his place in a Saracens starting line-up tomorrow also featuring Paddy Johns and Paul Wallace.
(Rugby Union) Straeuli takes charge at Bedford