The first landmark US federal opioid trial is set to begin Monday after furious, last-minute settlement talks  faltered. Photograph: Ty Wright

Drugmaker Teva Pharmaceuticals and three distributors of opioid painkillers reached a settlement with two US counties over their alleged role in the o(...)

Tributes placed in front of the office where lawyer Derk Wiersum was shot dead, in Amsterdam. Photograph: EPA/Koen Van Weel

Given that the Netherlands has a well-rooted illegal drugs industry, with Rotterdam as its trans-shipment hub, there was some surprise last week when (...)

The ruling by an Oklahoma judge that Johnson & Johnson intentionally played down the dangers and oversold the benefits of opioids is an important milestone in the campaign to make drug companies accountable for their role in creating the prescription painkiller epidemic in the United States. Photograph: Justin Lane/EPA

The ruling by an Oklahoma judge that Johnson & Johnson intentionally played down the dangers and oversold the benefits of opioids is an important (...)

Mexican drug lord Joaquin ‘El Chapo’ Guzman escorted by authorities after his detention, in Mexico City, Mexico, in May 2016.  File photograph: Jose Mendez/EPA

Joaquín “El Chapo” Guzmán, the Mexican drug lord who twice escaped maximum-security prisons in that country, will spend the rest of his life in a US p(...)

Sinaloa state police agents stand guard during a security operation in the city of Culiacan, Sinaloa state, Mexico, on February 15th. Photograph: Rashide Frias/AFP/Getty Images)

President Andrés Manuel López Obrador received a blunt warning earlier this month: a crude hand-painted sign strung up on a bridge in the border city (...)

 Joaquin “El Chapo” Guzmán:  seemed ecstatic to see actor Alejandro Edda, who plays him on Netflix’s “Narcos: Mexico” in court. Photograph:  Eduardo Verdugo/AP

After a lengthy 11-week trial in Brooklyn, New York, a jury on Monday began deliberating the case of Joaquín Guzmán Loera, the Mexican drug kingpin k(...)

Those charged in the Rhoden family homicides

After 550 interviews and visits to 10 states, including a 10,000km round-trip to Alaska, criminal investigators in Ohio are closing in on solving one (...)

The documents sketch a picture of how Prince, a strict proponent of clean living who suffered from chronic hip pain, concealed his opioid addiction using a variety of methods. Photograph: Jumana  El-Heloueh/Reuters

At the time of Prince’s death, his Paisley Park home and recording compound in Minnesota were strewn with “a sizeable amount” of narcotic painkillers (...)

A suitcase filled with blocks of hashish, seized from the cargo ship Munzur in December  2015, in the office of the Guardia di Finanza, the Italian financial police force, in Palermo, Italy, in June.  Photograph: Gianni Cipriano/The New York Times

The investigators for Italy’s anti-drug unit were used to measuring the flow of hashish from Moroccan fields to European shores one speedboat or Jet (...)

The bitcoin to be auctioned are worth about $1.6 million, according to the Bitstamp exchange

The US government said on Monday it planned to auction more than 2,700 bitcoin forfeited during several cases, including the prosecution of the creato(...)

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