Arsenal (1) v Norwich (18)
Arsenal expect Mesut Ozil to have recovered from a knee injury. Fellow midfielder Santi Cazorla could also return for the first time since September following an ankle injury, while full-back Bacary Sagna (hamstring) may also be involved. Forward Theo Walcott (abdominal), Yaya Sanogo (back), Lukas Podolski (hamstring), Alex Oxlade-Chamberlain and Abou Diaby (both knee) are all still recovering.
Forward Anthony Pilkington made an early return from Republic of Ireland duty due to a hamstring injury, but Chris Hughton is optimistic he will be fit. The Canaries boss will assess a number of other knocks ahead of the trip.
Last season: Arsenal 3 Norwich 1, Norwich 1 Arsenal 0
Last five league matches: Arsenal W W W W D; Norwich W L L W L
Top scorers: Aaron Ramsey (Arsenal) 8; Anthony Pilkington, Gary Hooper, Johan Elmander & Steven Whittaker (Norwich) 2
Match Odds: H 2-7 A 9-1 D 9-2
Referee: Lee Probert (Wiltshire).
Chelsea (3) v Cardiff (14)
Frontman Fernando Torres could return from a knee injury sooner than expected, but left-back Ashley Cole (ribs) and forward Andre Schurrle (leg) are out. Cole is set to be replaced by Ryan Bertrand, while Schurrle is not fit despite performing well with Germany. Goalkeeper Petr Cech is expected to make his 300th Chelsea appearance.
Striker Andreas Cornelius, who has been sidelined since August, remains the only injury absentee as Cardiff look to move on from recent off-field events. Manager Malky Mackay may again opt for Peter Odemwingie over Craig Bellamy in attack following the latter's exertions for Wales, while Jordon Mutch is in contention for a midfield berth.
Last season: No corresponding fixture
Last five league matches: Chelsea D L W D W; Cardiff D D L W L
Top scorers: Oscar (Chelsea) 4; Peter Odemwingie & Fraizer Campbell (Cardiff) 2
Match Odds: H 1-4 A 10-1 D 5-1
Referee: Anthony Taylor (Cheshire).
Everton (7) v Hull (8)
Everton midfielder Darron Gibson has been ruled out for several months after rupturing a cruciate knee ligament. Steven Pienaar (hamstring) is still a week away from full recovery and defender Antolin Alcaraz (hernia) at least three weeks off. On-loan midfielder Gareth Barry returns after being ineligible to face Manchester City.
Hull's top-scorer Robbie Brady is set for a swift return having missed only one match since a hernia operation. Ahmed Elmohamady, Gedo and Maynor Figueroa will be assessed after all had long journeys back from international duty. Robert Koren (fractured foot) and James Chester (hamstring) are still out.
Last season: No corresponding fixture
Last five league matches: Everton D W W W L; Hull L D W W D
Top scorers: Romelu Lukaku (Everton) 4; Robbie Brady (Hull) 4
Match Odds: H 4-9 A 7-1 D 16-5
Referee: Neil Swarbrick (Lancashire).
Man Utd (9) v Southampton (4)
Robin van Persie and Wayne Rooney look certain to start in attack for Manchester United after both scored during the international break, but Tom Cleverley is likely to miss out after picking up a calf injury prior to England's victory over Montenegro. Manager David Moyes' major decision appears to revolve around 18-year-old Adnan Januzaj, who netted a match-winning brace on his full Premier League debut at Sunderland a fortnight ago.
Artur Boruc and Luke Shaw are both in contention for Southampton. Saints boss Mauricio Pochettino expects Boruc to start in goal, despite the Poland physio claiming he suffered a hamstring injury during the international break. Shaw was unable to link up with the England Under-21s due to illness but is also in contention, while Gaston Ramirez will be assessed after arriving back from Uruguay duty late on Thursday.
Last season: Man Utd 2 Southampton 1, Southampton 2 Man Utd 3
Last five league matches: Man Utd L W L L W; Southampton L D W W W
Top scorers: Robin van Persie (Man Utd) 6; Steven Davis, Gaston Ramirez, Jay Rodriguez & Rickie Lambert (Southampton) 2
Match Odds: H 11-20 A 5-1 D 3-1
Referee: Mike Jones (Cheshire).
Newcastle (11) v Liverpool (2)
Newcastle will be without defender Fabricio Coloccini and fellow Argentinian Jonas Gutierrez. Coloccini has been ruled out with a groin injury, while midfielder Gutierrez has been allowed to return to his native country for personal reasons. Steven Taylor is unlikely to have recovered in time from a hamstring problem, so Mapou Yanga-Mbiwa is in line to start.
Defenders Glen Johnson and Aly Cissokho return to Liverpool's squad after lengthy injury lay-offs. Joe Allen (hamstring) is also back while fellow midfielder Lucas Leiva is included after suspension. Only Philippe Coutinho (shoulder) is out.
Last season: Newcastle 0 Liverpool 6, Liverpool 1 Newcastle 1
Last five league matches: Newcastle W W L L W; Liverpool W D L W W
Top scorers: Loic Remy (Newcastle) 5; Daniel Sturridge (Liverpool) 8
Match Odds: H 16-5 A 5-6 D 13-5
Referee: Andre Marriner (W Midlands).
Stoke (16) v West Brom (12)
Full-back Geoff Cameron is Stoke's only doubt, having picked up a calf probleme on United States duty. Forward Jon Walters pulled out of the Republic of Ireland squad for their World Cup qualifiers against Germany and Kazakhstan due to a groin complaint but he is fit to feature tomorrow.
West Brom head coach Steve Clarke hopes to have a largely injury-free squad at his disposal. He has only two definite absentees in the shape of goalkeeper Ben Foster (foot) and winger Scott Sinclair (hamstring). Matej Vydra, Victor Anichebe, Shane Long and Zoltan Gera are all available after recent injuries.
Last season: Stoke 0 West Brom 0, West Brom 0 Stoke 1
Last five league matches: Stoke W D L L L; West Brom L D W W D
Top scorers: Kenwyne Jones (Stoke) 3; Saido Berahino (West Brom) 5
Match Odds: H 13-10 A 9-4 D 11-5
Referee: Howard Webb (S Yorkshire).
Swansea (15) v Sunderland (20)
Swansea captain Ashley Williams will again be missing due to an ankle ligament injury, while left-back Ben Davies is a doubt as a result of the hamstring injury he picked up against Southampton. But Michel Vorm (hand), Pablo Hernandez (hamstring) and Jonathan de Guzman (groin) are all set to feature.
Sunderland striker Steven Fletcher will return to the squad — ahead of schedule - after missing the last three games with a shoulder injury and could feature in new boss Gus Poyet's first game. Goalkeeper Keiren Westwood (shoulder) and defenders Wes Brown (calf) and Phil Bardsley (foot) could be back too, but midfielder Ki Sung-yueng is ineligible against his parent club.
Last season: Sunderland 0 Swansea 0, Swansea 2 Sunderland 2
Last five league matches: Swansea W D W L L; Sunderland L L L L L
Top scorers: Wilfried Bony & Miguel Michu (Swansea) 5; Emanuele Giaccherini (Sunderland) 3
Match Odds: H 4-7 A 5-1 D 14-5
Referee: Craig Pawson (South Yorkshire).
West Ham (13) v Man City (5)
West Ham defender James Collins will miss the game after suffering a hamstring injury in Wales' 1-1 midweek draw against Belgium. He joins Andy Carroll (heel) and Alou Diarra (knee) on the sidelines, while Carlton Cole is not fit enough to be involved.
Manchester City captain Vincent Kompany (thigh) is making good progress but will not be risked while fellow centre-back Martin Demichelis (knee), who is still to make his debut, is also not yet fit. Midfielder Jack Rodwell (hamstring) is back in contention.
Last season: Man City 2 West Ham 1, West Ham 0 Man City 0
Last five league matches: West Ham L D L L W; Man City W D W L W
Top scorers: Ravel Morrison (West Ham) 4; Yaya Toure (Man City) 6
Match Odds: H 4-1 A 7-10 D 11-4
Referee: Michael Oliver (Northumberland).
Aston Villa (10) v Tottenham (6)
Villa boss Paul Lambert will make a late decision on striker Christian Benteke, who has been out since September with a hip injury but trained with Belgium earlier this week and was an unused substitute against Wales on Tuesday. Jores Okore (cruciate ligament) and midfielder Charles N'Zogbia (Achilles) are long-term casualties.
Tottenham winger Aaron Lennon has recovered from a foot injury and is in contention. Left-back Danny Rose (toe) and midfielder Etienne Capoue (ankle) are out until next week, while defender Younes Kaboul is doubtful because of an adductor injury.
Last season: Aston Villa 0 Spurs 4, Spurs 2 Aston Villa 0
Last five league matches: Aston Villa L L W W D; Spurs L W W D L
Top scorers: Christian Benteke (Aston Villa) 5; Jermain Defoe (Spurs) 7
Match Odds: H 13-5 A 21-20 D 12-5
Referee: Phil Dowd (Staffordshire).
Crystal Palace (19) v Fulham (17)
Palace manager Ian Holloway has no fresh injury concerns. Yannick Bolasie is pushing for a first league start, having come off the bench in the 3-1 defeat at Liverpool before the international break. Club captain Paddy McCarthy has returned to training after a prolonged spell on the sidelines with a groin injury, but Glenn Murray (knee) remains absent.
Midfielder Scott Parker could be back in Fulham's line-up following a calf problem. Defender Aaron Hughes will train with the squad as he continues his recovery from a thigh injury, and manager Martin Jol has also declared forward Adel Taarabt fit.
Last season: No corresponding fixture
Last five league matches: Crystal Palace W L L L L; Fulham L D L L W
Top scorers: Dwight Gayle (Crystal Palace) 2; Darren Bent (Fulham) 3
Match Odds: H 13-8 A 17-10 D 9-4
Referee: Lee Mason (Lancashire).