Today
Arsenal (5) v Bolton (12)
Tony Adams will not play for Arsenal despite recovering from a rib injury - manager Arsene Wenger is keeping him back for Tuesday's UEFA Cup tie in Greece against PAOK Salonika. Dennis Bergkamp will spearhead Arsenal's attack alongside Ian Wright, but has confirmed he will not travel to the European game.
Bolton defender Neil Cox is out with a hamstring injury, but Gerry Taggart has reported fit. Jimmy Phillips and Mark McAnespie are expected to be given the full-back roles. New £2 million signing from Lazio Mark Fish still awaits a work permit.
Last season: No corresponding fixtures
Last five League matches: Arsenal DWWDD, Bolton DWDLD
Top scorers: Dennis Bergkamp (Arsenal) 5, Nathan Blake (Bolton) 3
Match odds: H 4-9 A 6-1 D 5-2
Referee: N S Barry (Scunthorpe)
Barnsley (10) v Aston Villa (19)
Barnsley's new £1.3 million striker Ashley Ward will make his debut alongside Macedonian international Georgi Hristov. German goalkeeper Lars Leese retains his place in goal with David Watson still injured (bruised kidneys)
Sasa Curcic is pressing for a place in the Aston Villa starting line-up, but will only play if Ian Taylor fails to shake off a groin strain.
Last season: No corresponding fixtures
Last five League matches: Barnsley LWLWL, Aston Villa LLLLW
Top scorers: Neil Redfearn (Barnsley) 2; Dwight Yorke (Aston Villa) 2
Match odds: H 7-4 A 5-4 D 9-4
Referee: G P Barber (Pyrford)
Coventry (13) v Southampton (18)
Gary McAllister is recalled to Coventry's midfield, taking over from Kevin Richardson, who signed for Southampton on Tuesday. The Scotland captain has not played for the club since damaging an ankle against Arsenal in the second match of the season four weeks ago.
Richardson will captain Southampton on his debut against his old club. Norwegian international Claus Lundekvam, midfielder Matthew Oakley and defender Richard Dryden are in contention for a return after injury, but Francis Benali is struggling.
Last season: Coventry 1-1 Southampton, Southampton 2-2 Coventry
Last five League matches: Coventry WLDDL, Southampton LLLWL
Top scorers: Dion Dublin (Coventry) 3; Kevin Davies (Southampton) 2
Match odds: H 10-11 A 5-2 D 9-4
Referee: U D Rennie (Sheffield)
Crystal Palace (9) v Chelsea (4)
Palace have injury doubts over Simon Rodger, Paul Warhurst and Marc Edworthy as they aim to earn their first win at Selhurst Park this season.
Chelsea boss Ruud Gullit could pair Mark Hughes and Gianluca Vialli up front, to rest Gianfranco Zola and Tore Andre Flo after their international duty. Frank Sinclair begins a threematch suspension with Steve Clarke favourite to come in, although Gullit has named himself in the squad.
Last season: No corresponding fixtures
Last five League matches: Crystal Palace WLWLL, Chelsea DLWWW
Top scorers: Bruce Dyer, Attilio Lombardo (Crystal Palace) 2; Gianluca Vialli (Chelsea) 4
Match odds: H 2-1 A 11-10 D 9-4
Referee: G R Ashby (Worcester)
Derby (17) v Everton (14)
Derby's Croatian midfielder Aljosa Asanovic has fully recovered from the hamstring strain that forced him out of the opening games, although manager Jim Smith may draft in Costa Rican striker Paulo Wanchope instead.
Everton wing-back Terry Phelan is ruled out with a damaged calf, so Andy Hinchcliffe makes his first full appearance since December after knee and thigh injuries. Full-back Tony Thomas is also missing with a calf problem, while veteran defender Dave Watson is struggling with a damaged ankle. Tony Grant and youngster Danny Cadamarteri are added to the squad.
Last season: Derby 0-1 Everton, Everton 1-0 Derby
Last five League matches: Derby WLLLW, Everton LLWLD
Top scorers: Stefano Eranio (Derby) 1; Gary Speed, Graham Stuart, Duncan Ferguson (Everton) 1
Match odds: H 5-4 A 7-4 D 9-4
Referee: M A Riley (Leeds)
Leicester (6) v Tottenham (7)
Tony Cottee could be in line for his full Leicester debut in partnership with Emile Heskey. Garry Parker has shaken off a stomach bug and manager Martin O'Neill has no other injury worries.
Spurs' Norwegian striker Steffen Iversen is definitely out with an ankle injury, but Chris Armstrong could make his first appearance since December.
Last season: Leicester 1-1 Tottenham, Tottenham 1-2 Leicester
Last five League matches: Leicester WWDDL, Tottenham LLWWD
Top scorers: Matt Elliott (Leicester) 2; Les Ferdinand (Tottenham) 3
Match odds: H 11-8 A 13-8 D 11-5
Referee: A B Wilkie (Chester-le-Street)
Liverpool (11) v Sheffield Wed (16)
Norwegian midfielder Oyvind Leonhardsen has not recovered from a hamstring injury. Robbie Fowler is still out and Patrik Berger is pushing for a first-team spot. Wednesday manager David Pleat is set to hand debuts to new midfielder Jim Magilton and loan signing Nigel Clough. Strikers Andy Booth and Ritchie Humphreys are still out injured.
Last season: Liverpool 0-1 Sheff Wed, Sheff Wed 1-1 Liverpool
Last five League matches: Liverpool DDLDW, Sheff Wed LLDLW
Top scorers: Michael Owen (Liverpool) 2; Benito Carbone (Sheff Wed) 4
Match odds: H 1-2 A 11-2 D 12-5
Referee: G Poll (Tring)
Manchester Utd (2) v West Ham (3)
Andy Cole and Paul Scholes look certain to play for Manchester United with Teddy Sheringham out with broken ribs. Ronny Johnsen comes into contention in defence.
Steve Potts returns to the West Ham side with Marc Rieper going to Celtic. French triallist David Terrier, who played at centre half for Metz last year, is also included in the squad as cover.
Last season: Man Utd 2-0 West Ham, West Ham 2-2 Man Utd
Last five League matches: Man Utd WDWW, West Ham WWLDW
Top scorers: David Beckham (Man Utd) 2; John Hartson (West Ham) 3
Match odds: H 4-9 A 6-1 D 5-2
Referee: D R Elleray (Harrow-on-the-Hill)
Newcastle (8) v Wimbledon (20)
Kenny Dalglish is hinting at changing his line-up, but will wait for Faustino Asprilla to return from World Cup duty before finalising his team. David Batty is suspended, while Stuart Pearce and Darren Peacock will have fitness tests.
Dons' boss Joe Kinnear has added young striker Carl Cort to the squad after his success in the youth side and reserves. Ex-England under-21 captain Ben Thatcher and Vinnie Jones both available after missing the last match.
Last season: Newcastle 2-0 Wimbledon, Wimbledon 1-1 Newcastle
Last five League matches: Newcastle DDWWW, Wimbledon WDDLL
Top scorers: John Beresford, Faustino Asprilla (Newcastle) 3; Marcus Gayle, Efan Ekoku, Jason Euell (Wimbledon) 1
Match odds: H 4-9 A 6-1 D 5-2
Referee: M D Reed (Birmingham)
Tomorrow
Blackburn (1) v Leeds (15)
Blackburn are without centre back Ian Pearce, sidelined by a calf injury, and Billy McKinlay, who suffered a recurrence of his groin injury while on international duty with Scotland. Colin Hendry has been given the all clear after suffering concussion against Crystal Palace and Jason Wilcox has fully recovered from a knock on his ribs.
Leeds manager George Graham is playing his cards close to his chest but is unlikely to make sweeping changes, although Lee Bowyer could return to midfield after sitting out the last two games on the bench.
Last season: Blackburn 0-1 Leeds, Leeds 0-0 Blackburn
Last five League matches: Blackburn WWDWW, Leeds DWLLL
Top scorers: Chris Sutton (Blackburn) 6; Rod Wallace (Leeds) 2
Match odds: H 8-13 A 4-1 D 12-5
Referee: S W Dunn (Bristol)