Portuguese police want to reinterview the mother of Madeleine McCann so they can ask her more than 40 questions she previously refused to answer, it has been reported.
Kate McCann remained silent when detectives initially put the questions to her in the presence of her lawyer, according to the Portuguese newspaper Publico.
Kate McCann's diary is believed to contain details about the night Madeline went missing
Police also want fresh interviews with some of the friends on holiday in Portugal with her and her husband Gerry when Madeleine went missing from the family's holiday apartment in the Algarve resort of Praia da Luz on May 3rd, according to separate reports.
Mrs McCann's private diary documents her struggles to look after her "hysterical" children and reveals details about the night Madeleine went missing, it was reported.
The diary is among a number of personal items prosecutors want from the parents, sources said. Mrs McCann was frequently seen writing her journal in private moments after Madeleine went missing.
She also complains her husband does not help with family chores, meaning that the burden of looking after their twins falls on her, according to the Correio da Manha. Although she does not confess to any crimes in the diary, it is considered "fundamental" to the investigation, the paper said.
Senior sources linked to the investigation told Portuguese journalists they discovered "bodily fluids" - not blood - with an 88 per cent match to Madeleine's genetic profile in the boot of hire car rented by her parents 25 days after she went missing.
Toxicological tests on the liquid show that Madeleine had consumed a "significant" quantity of sleeping tablets and may have overdosed, the French newspaper France Soirreported.
Social workers visited the McCanns at home yesterday after the couple invited them for talks about their two-year-old twins.