The repercussions of Liverpool's defeat at Southampton on Sunday were clear when Gerard Houllier left out Stephane Henchoz, El-Hadji Diouf and Milan Baros and brought in Emile Heskey, Danny Murphy and John Arne Riise for tonight's match with Portsmouth.
Jamie Carragher switched from left to right-back to let the Norwegian into defence, while Igor Biscan played in central defence.
Portsmouth had Svetoslav Todorov in their side for the first time this season, the Bulgarian damaging his knee ligaments two days before the campaign, while Alexei Smertin returned for the Hampshire side after suspension.
Liverpool: Dudek, Carragher, Biscan, Hyypia, Riise, Murphy, Hamann, Gerrard, Kewell, Owen, Heskey. Subs: Henchoz, Baros, Diouf, Cheyrou, Luzi Bernardi.
Portsmouth: Hislop, Stefanovic, Primus, De Zeeuw, Curtis, Smertin, Faye, Hughes, LuaLua, Todorov, Mornar. Subs: Wapenaar, Taylor, Sheringham, Stone, Pasanen.