SATURDAY (3.0 unless stated)
Bournemouth (16) v Man City (5), 12.30pm - Sky Sports Main Event & Premier League
Jermain Defoe could retain his place up front when Bournemouth host Manchester City. Defoe played 90 minutes at Birmingham in the Carabao Cup in midweek and Cherries boss Eddie Howe was impressed with his performance. Howe has no fresh injury concerns but captain Simon Francis (hamstring) and midfielder Junior Stanislas (groin) remain sidelined, along with long-term absentee Callum Wilson (knee).
Manchester City will be without Kyle Walker through suspension after he was controversially sent off in Monday's draw against Everton. The right back is set to be replaced in the line-up by fellow new signing Danilo. Left back Benjamin Mendy (thigh) will travel with the squad but the game may come too soon, while midfielder Ilkay Gundogan (knee) will feature for the elite development squad.
Last season: Bournemouth 0 Man City 2, Man City 4 Bournemouth 0. Last five league matches: Bournemouth D W D L L; Man City W W W W D. Top scorers (all competitions): Ryan Fraser & Marc Pugh (AFC Bournemouth) 1; Sergio Aguero & Raheem Sterling (Man City) 1. Match odds: H 8-1 D 4-1 A 1-3. Referee: Mike Dean
Crystal Palace (19) v Swansea (15)
Ruben Loftus-Cheek has suffered a groin injury and joins Crystal Palace winger Wilfried Zaha (knee) on the sidelines. Midfielder James McArthur is pushing for his first league start of the season after scoring twice in the Carabao Cup victory over Ipswich in midweek.
Sam Clucas could go straight into the Swansea side at Crystal Palace following his £15 million move from Hull. Skipper Leon Britton is also available after a back injury forced him out of the last two games against Manchester United and MK Dons. But Kyle Bartley (knee ligaments) has joined a casualty list which includes Fernando Llorente (arm), Nathan Dyer (Achilles) and Ki Sung-yueng (knee).
Last season: Crystal Palace 1 Swansea 2, Swansea 5 Crystal Palace 4. Last five league matches: Crystal Palace L W L L L; Swansea W W W D L. Top scorers (all competitions): James McArthur (Crystal Palace) 2; Leroy Fer (Swansea) 2. Match odds: H 10-11 D 12-5 A 3-1. Referee: Andre Marriner.
Huddersfield (2) v Southampton (7)
Huddersfield manager David Wagner will not consider selecting new signings Abdelhamid Sabiri and Florent Hadergjonaj. Wagner wants midfielder Sabiri and right back Hadergjonaj to do some work in training before coming into contention for the trip to West Ham after the international break. The Terriers are still without midfielder Jonathan Hogg, forward Nahki Wells (both ankle) and defenders Martin Cranie (hip) and Jon Gorenc Stankovic (knee).
Dutch defender Wesley Hoedt could make his Southampton debut. The 23-year-old arrived at St Mary's on Tuesday for a reported £15million from Serie A club Lazio. Saints, however, will once again be without wantaway centre-back Virgil van Dijk, according to manager Mauricio Pellegrino.
Last season: No corresponding fixture. Last five league matches: Huddersfield W L L W W; Southampton W D L D W. Top scorers (all competitions): Steve Mounie (Huddersfield) 2; Charlie Austin, Manolo Gabbiadini & Dusan Tadic (Southampton) 1. Match odds: H 13-5 D 9-4 A 11-10. Referee: Stuart Attwell.
Newcastle (17) v West Ham (20), Live Sky Premier League
Newcastle winger Rolando Aarons (knock) is a doubt for the home clash with West Ham. Goaleeper Karl Darlow is out with a thigh problem, while Jonjo Shelvey completes his three-match ban and defenders DeAndre Yedlin and Paul Dummett (both hamstring) and Florian Lejeune (ankle ligaments) are still out.
Manuel Lanzini will be added to the West Ham squad for the trip to Newcastle after recovering from a knee injury. Andy Carroll is also back in training after his latest lay-off due to a thigh problem and will be assessed. Winston Reid (calf) is the only definite injury absentee while Marko Arnautovic is still suspended.
Last season: No corresponding fixture. Last five league matches: Newcastle W W W L L; West Ham W L W L L. Top scorers (all competitions): Rolando Aarons & Aleksandar Mitrovic (Newcastle) 1; Sead Haksabanovic & Javier Hernandez (West Ham) 2. Match odds: H 13-10 D 23-10 A 21-10. Referee: Neil Swarbrick (Lancashire).
Watford (4) v Brighton (18)
Watford could hand a debut to new loan signing Andre Carrillo after the Benfica winger joined the Hornets on Thursday. Younes Kaboul, Daryl Janmaat and Roberto Pereyra all suffered muscular injuries against Liverpool and are sidelined, as is Mauro Zarate (knee), while Jose Holebas is banned.
Brighton boss Chris Hughton may give a debut to record-signing Jose Izquierdo. Albion will not, however, be able to call on Ghana striker Raphael Dwamena at Vicarage Road as a work permit application is holding up his transfer from FC Zurich. Seagulls striker Glenn Murray (ankle) and midfielder Steve Sidwell (back) should be fit but Izzy Brown (hamstring), Beram Kayal (broken leg) and Sam Baldock (knee) remain out.
Last season: No corresponding fixture. Last five league matches: Watford L L L D W; Brighton L L D L L. Top scorers (all competitions): Richarlison (Watford) 4; James Tilley (Brighton) 1. Match odds: H 10-11 D 23-10 A 10-3. Referee: Graham Scott.
Manchester United (1) v Leicester (9), 5.30 – Live on BT Sport 1
Manchester United boss Jose Mourinho may opt to retain the same starting XI against Leicester. Luke Shaw and Ashley Young stepped up their recoveries from injury by playing for the under-23s this week but are not expected to be involved while Zlatan Ibrahimovic and Marcos Rojo (both knee) remain sidelined.
Captain Wes Morgan and striker Jamie Vardy could both be back in Leicester's starting line-up. Both players were left nursing injuries following the home win over Brighton but Morgan's back complaint has eased and Vardy is fit again after a foot problem. Danny Drinkwater (thigh) and Papy Mendy (ankle) have resumed full training while Kelechi Iheanacho has also been able to train but remains a doubt.
Last season: Leicester 0 Man Utd 3, Man Utd 4 Leicester 1. Last five league matches: Man Utd L D W W W; Leicester L L D L W. Top scorers (all competitions): Romelu Lukaku (Man Utd) 4; Shinji Okazaki, Islam Slimani & Jamie Vardy (Leicester) 2. Match odds: H 3-10 D 9-2 A 17-2. Referee: Michael Oliver.
Chelsea (12) v Everton (8), 1.30
Chelsea midfielder Cesc Fabregas returns from suspension but defender Gary Cahill is still banned following his red card against Burnley on the opening day of the season. Forward Eden Hazard is due to play for the club's under-23s on Friday as he builds up his fitness following a broken ankle.
Everton have doubts over both Idrissa Gueye (hamstring) and Sandro Ramirez (heel), and will be without Davy Klaassen (foot). Morgan Schneiderlin is suspended and James McCarthy, Ramiro Funes Mori, Yannick Bolasie (all knee), Séamus Coleman (broken leg) and Ross Barkley (hamstring) are on the sidelines.
Last season: Everton 0 Chelsea 3, Chelsea 5 Everton 0. Last five league matches: Chelsea W W W L W; Everton L W L W D. Top scorers (all competitions): Marcos Alonso (Chelsea) 2; Wayne Rooney (Everton) 2. Match odds: H 2-5 D 7-2 A 13-2. Referee: Jonathan Moss.
West Brom (3) v Stoke (14), 1.30 – Sky Sports Main Event & Premier League
Jonny Evans remains a doubt for West Brom because of a hamstring injury and he will continue to be assessed. Fellow centre half Gareth McAuley (thigh) remains out and striker Hal Robson-Kanu is still suspended. James Morrison will also be checked on after making his return from injury at Accrington. New signing Oliver Burke could be among the substitutes.
Xherdan Shaqiri remains an injury concern for Stoke after a hamstring problem forced him off midway through the first half of the home win against Arsenal. Jack Butland, Ryan Shawcross, Darren Fletcher, Rodriguez Jese and Eric Maxim Choupo-Moting are expected to come back into the team after the Carabao Cup win over Rochdale.
Last season: West Brom 1 Stoke 0, Stoke 1 West Brom 1. Last five league matches: West Brom L L L W W; Stoke D L W L W. Top scorers (all competitions): Ahmed Hegazi, Matt Phillips, Hal Robson-Kanu, Jay Rodriguez & Jose Rondon (West Brom) 1; Joe Allen (Stoke) 2. Match odds: H 29-20 D 2-1 A 21-10. Referee: Anthony Taylor.
Liverpool (6) v Arsenal (11), 4.0 – Sky Sports Main Event & Premier League
Liverpool are again without Philippe Coutinho for Arsenal's visit. Reds boss Jürgen Klopp confirmed the Barcelona target is still "on our injury list" with a back problem. Klopp is hopeful that both Emre Can and Trent Alexander-Arnold can overcome minor issues while Georginio Wijnaldum is set to return but Nathaniel Clyne (hamstring) and Adam Lallana (thigh) remain absent.
Alexis Sanchez is in line to make his first Arsenal appearance of the season. The Chile international has been absent with an abdominal strain but is set to be involved, as is defender Laurent Koscielny who returns from a three-match ban. Santi Cazorla (ankle) still sidelined.
Last season: Liverpool 3 Arsenal 1, Arsenal 3 Liverpool 4. Last five league matches: Liverpool D W W D W; Arsenal W W W W L. Top scorers (all competitions): Emre Can, Roberto Firmino, Sadio Mane & Mohamed Salah (Liverpool) 2; Olivier Giroud, Sead Kolasinac, Alexandre Lacazette, Aaron Ramsey & Danny Welbeck 1. Match odds: H 23-20 D 13-5 A 11-5. Referee: Martin Atkinson.
Tottenham (10) v Burnley (13), 4.0
Tottenham remain hopeful that club-record signing Davinson Sanchez will receive a work permit in time to feature against Burnley. The Colombia international defender joined Spurs from Ajax but may be forced to sit out the meeting at Wembley if his permit is not issued in time. Georges-Kevin Nkoudou (foot), Danny Rose (knee) and Erik Lamela (hips) have progressed in their respective recoveries but are all still missing.
Summer signing Jonathan Walters (ankle) is out while midfielder Jeff Hendrick is a doubt with a thigh strain. However, record signing Chris Wood, who joined the club in a £15 million switch from Leeds earlier this week, could be handed his first start after replacing Walters at Ewood Park, where manager Sean Dyche made eight changes.
Last season: Burnley 0 Tottenham 2, Tottenham 2 Burnley 1
Last five league matches: Tottenham W W W W L; Burnley D L L W L
Top scorers (all competitions): Dele Alli & Ben Davies (Tottenham) 1; Sam Vokes (Burnley) 2
Match odds: H 1-4 D 9-2 A 12-1
Referee: Lee Mason