England captain Michael Vaughan has been ruled out for the rest of the current Test series against India.
His knee problem, which flared up again last week, also makes Vaughan's participation in the one-day matches unlikely.
The Yorkshire star flew home earlier this week to have the problem in his right knee assessed by the specialist in Sheffield who operated on the joint in December.
After undergoing an ultrasound-guided injection in the knee, Vaughan has been advised to take it easy for the next fortnight.
"The specialist has advised Michael to rest the knee completely for two weeks before recommencing his rehabilitation programme under the supervision of the Yorkshire Country Cricket Club physiotherapist," said an England and Wales Cricket Board statement.
"Michael has been ruled out of the current Test series against India. His knee will be reassessed in due course but at this stage it is not anticipated that he will be fit for the one-day international series in India."