Glenn Hoddle's tenure at Tottenham reached a new low as they were beaten 3-1 at home to Southampton.
Hoddle has faced increasing speculation over his future after a poor start to the season which saw Spurs gather just four points from five games before today.
And James Beattie turned up the pressure by scoring his fifth and sixth goals of the season to give Saints a 2-0 half-time lead.
The England international headed home a Matt Oakley corner to give Hoddle's former team the lead after just three minutes and he netted a second before the break.
Kevin Phillips made it three on the hour mark and, although Frederic Kanoute pulled a goal back for the home side two minutes later, Spurs left the field to boos and cat-calls while Southampton left with the points.
Chelsea's 5-0 win over Wolves after an early kick-off took them to the top of the Barclaycard Premiership on goal difference.
Manchester City could have claimed their place at the top of the table by beating Fulham by more than three goals in the capital.
The visitors did score through Nicolas Anelka, who found the back of the net a minute into the second half.
But Steed Malbranque equalised and Louis Saha put Chris Coleman's outfit ahead - only for Paulo Wanchope to net a late equaliser as City happily settled for a 2-2 draw.
Liverpool shrugged off the loss of Milan Baros and Jamie Carragher to injury in midweek to take the lead against Leicester at Anfield through a Michael Owen penalty in the 20th minute.
Vladimir Smicer earned the spot-kick, drawing a foul from Leicester's Ben Thatcher.
Emile Heskey wrapped up the victory with a second goal after 75 minutes with Marcus Bent's stoppage time strike mere consolation for Leicester.
Lucas Neill gave former Anfield chief Graeme Souness a reason to be thankful for his presence in a blue and white jersey by netting the opener at Portsmouth after 35 minutes.
A 43rd-minute effort from Andy Cole meant Rovers were cruising and, although Arjan De Zeeuw pulled a goal back for Pompey after 57 minutes, Blackburn earned the 2-1 victory.
Birmingham inflicted more misery on Leeds with Robbie Savage netting either side of Roque Junior's sending off to earn the Elland Road visitors a 2-0 lead.
Turkey international Alpay gave Aston Villa a 1-0 lead after 37 minutes against Charlton with a close-range right-foot volley.
And a Jlloyd Samuel's strike 10 minutes into the second half put the game out of reach for Charlton who managed a late consolation through Kevin Lisbie. Bolton held