AstraZeneca targets two billion doses of coronavirus vaccine

British drugmaker AstraZeneca has doubled manufacturing capacity for its potential coronavirus vaccine to two billion doses in two deals involving Microsoft billionaire Bill Gates that guarantee early supply to lower-income countries.

The deals with epidemic response group CEPI and vaccine alliance GAVI are backed by the World Health Organisation and aim to quell concerns that the company was committing all initial supplies of the vaccine to the developed world.

It is unclear if vaccines will work against coronavirus but dozens of companies are in the race to develop one, and AstraZeneca’s partnership with Oxford University is one of a handful to be backed so far by US president Donald Trump’s Covid-19 task force.

The White House in May secured 300 million of the first doses of the potential vaccine, named AZD1222, in a deal that also committed more than $1 billion in backing to testing and manufacturing. Britain previously booked another 100 million.

Trinity Biotech expects Covid-19 immunity test to be authorised shortly

---

Revenue faces US drug company Perrigo over disputed €1.64bn tax bill

---

Coronavirus: Irish firm LetsGetChecked offering home tests in US

---

Regeneron to create 60 new jobs in Limerick

---

Under Thursday's deals, the company will supply 300 million doses, starting this year, to CEPI and GAVI, as it aims at fair and equitable distribution of the vaccine, chief executive Pascal Soriot said.

Largest manufacturer

He said AstraZeneca had also agreed terms with the Serum Institute of India, the world’s largest manufacturer of vaccines by volume, to supply one billion doses for low- and middle-income countries.

An unspecified part of the vaccine doses produced by Serum will be used in India, with the remainder again to be distributed by GAVI in other lower-income countries, the company said on a call with journalists.

That leaves AstraZeneca with 300 million doses in planned production capacity, which has yet to be earmarked for use.

Astra is open for partners to sponsor even more volumes but it may be nearing a ceiling with plans laid out so far because the risk should be spread across different vaccine technologies, Soriot said.

Experts predict a safe and effective vaccine could take 12-18 months to develop.

The vaccine, previously known as ChAdOx1 nCoV-19, was developed by the University of Oxford and licensed to AstraZeneca.

Evidence of immunity to the new coronavirus has yet to be produced in ongoing trials but production will start nonetheless to be ready for mass rollout once regulatory approval is given.

Soriot did not comment on the odds of the compound being proven safe and effective, but added that trial results could be available in August, if enough trial participants caught the virus to yield reliable numbers.

“You can’t spend your time wondering is it going to work. We have to commit. That’s what we do in the industry, we bet on something. We are completely committed to the vaccine programme to deliver,” Soriot said. – Reuters