England have selected a new front row of Joe Marler, Dylan Hartley and David Wilson for Saturday's match against Argentina at Twickenham.
Marler replaces loosehead Mako Vunipola, who started the 20-13 victory over Australia but been sidelined by a knee ligament strain, and Hartley comes in for Tom Youngs at hooker.
Completing the front row overhaul is Wilson's promotion to the starting XV ahead of Dan Cole, who drops to the bench where he is joined by Youngs and Alex Corbisiero.
Corbisiero returns to the 23 after overcoming a knee problem, although he was expected to start the second match of England’s autumn series instead of Marler.
The fourth and final change, and the only adjustment to the backline, sees Ben Foden named on the left wing after Marland Yarde and Christian Wade were ruled out through injury.
Yarde has a hip complaint and Wade has incurred a hamstring injury.
"Christian was in contention for a start but his hamstring tightened up in training and unfortunately he hasn't recovered sufficiently in time to be considered," England coach Stuart Lancaster said.
"Marland this morning failed a fitness test on a hip injury sustained last weekend so Ben Foden gets his chance with Alex Goode on the bench.
“Ben has had a full week’s training on the wing, he is a great finisher and in form so it’s a great option for us.”
England (v Argentina): M Brown (Harlequins); C Ashton (Saracens), J Tomkins (Saracens), B Twelvetrees (Gloucester Rugby), B Foden (Northampton); O Farrell (Saracens), L Dickson (Northampton Saints); J Marler (Harlequins), D Hartley (Northampton Saints), D Wilson (Bath Rugby), J Launchbury (London Wasps), C Lawes (Northampton Saints), T Wood (Northampton Saints), C Robshaw (Harlequins, capt), B Vunipola (Saracens). Replacements: T Youngs (Leicester Tigers), A Corbisiero (Northampton Saints), D Cole (Leicester Tigers), G Parling (Leicester Tigers), B Morgan (Gloucester Rugby), B Youngs (Leicester Tigers), T Flood (Leicester Tigers), A Goode (Saracens).