Ireland coach Eddie O'Sullivan has recalled winger Justin Bishop into a side that sees three changes for this weekend's clash with Wales at the Millienium Stadium in Cardiff.
Leo Cullen and Alan Quinlan are also included in the place of the injured Gary Longwell and Victor Costello, respectively.
London Irish winger Bishop has not yet figured in this year's RBS Six Nations campaign but is an experienced international with 22 caps and eight tries for Ireland, the most recent coming against Fiji late last year.
Leinster's Eric Miller and Munster's Donncha O'Callaghan have secured places on the bench as cover. David Humphreys is again preferred to Ronan O'Gara despite a patchy performance against France.
15. Geordan Murphy (Leicester)
14. Justin Bishop (London Irish)
13. Brian O'Driscoll (Blackrock College/Leinster) - capt
12. Kevin Maggs (Bath)
11. Denis Hickie (St Mary's College/Leinster)
10. David Humphreys (Dungannon/Ulster)
9. Peter Stringer (Shannon/Munster)
1. Marcus Horan (Shannon/Munster)
2. Shane Byrne (Blackrock College/Leinster)
3. John Hayes (Shannon/Munster)
4. Leo Cullen (Blackrock College/Leinster)
5. Malcolm O'Kelly (St Mary's College/Leinster)
6. Alan Quinlan (Shannon/Munster)
7. Keith Gleeson (St Mary's College/Leinster)
8. Anthony Foley (Shannon/Munster).
Replacements.
16. Frank Sheahan (Cork Constitution/Munster)
17. Justin Fitzpatrick (Dungannon/Ulster)
18. Donncha O'Callaghan (Cork Constitution/Munster)
19. Eric Miller (Terenure College/Leinster)
20. Guy Easterby (Llanelli)
21. Ronan O'Gara (Cork Constitution/Munster)
22. John Kelly (Cork Constitution/Munster).