Chris Jones will make his first Test match start for England when they take on Scotland in the Calcutta Cup clash at Murrayfield this Saturday.
The 23-year-old Sale Sharks forward replaces Wasps flanker Joe Worsley, who is sidelined because of a hamstring injury.
It is the solitary change made by head coach Sir Clive Woodward following England's 50-9 victory over Italy last weekend in their RBS Six Nations opener.
Jones went on as a second-half substitute at Stadio Flaminio, scoring the last of England's seven tries. Jones' place on the bench is taken by his Sharks team-mate Alex Sanderson.
Scrum-half Andy Gomarsall has recovered from a thigh strain to retain the number nine jersey, while skipper Lawrence Dallaglio and centre Jason Robinson also feature after suffering minor hand injuries in Rome.
England: I Balshaw, J Lewsey, W Greenwood, J Robinson, B Cohen, P Grayson, A Gomarsall, T Woodman, S Thompson, P Vickery, D Grewcock, B Kay, C Jones, R Hill, L Dallaglio (capt)
Replacements: M Regan, J Leonard, S Shaw, A Sanderson, M Dawson, O Barkley, H Paul.