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‘It is clear that a welcome new mood of experimentation is afoot. Like so much else in the pandemic, it is impossible to know how it will end.’ Photograph: Getty Images

Among the many things I have failed to do in my career, there is one that I seriously regret. I have never been on a corporate retreat. Nor have I bee(...)

The Grange Castle plant, originally built by Wyeth before it merged with Pfizer, is state-of-the-art and has plenty of space for expansion. Photograph: Dara Mac Dónaill

Pfizer’s announcement that it will build a new vaccines business at its Grange Castle plant in Dublin is that rarity – unadulterated good news. Alongs(...)

The pandemic has fuelled a lack of camaraderie, but research suggests putting everyone back in the office again won’t entirely fix the problem.

Every other week or so, a number emerges somewhere in the world that I find both understandable and troubling. It is the percentage of people who con(...)

‘Your son and his wife should be able to access a mortgage. However, the situation is complicated by Covid.’

My son and his wife are living with us. They have €30,000 saved. They take home about €700 a week on account of the pandemic. Is there anyone out ther(...)

  AstraZeneca    is expected to quickly publish updated figures showing the vaccine boasts efficacy of between 69 and 74 per cent. Photograph: Fabio Ferrari/LaPresse via AP

An “unforced error” was the somewhat charitable comment by Dr Anthony Fauci, chief medical adviser to US president Joe Biden on “misleading” data issu(...)

‘Revenue is saying that my husband needs to submit accounts, in order for me to get a statement in relation to my employment.’ Photograph: Getty Images/iStockphoto

My husband is self-employed and I am a PAYE worker. Revenue will not issue me my 2020 preliminary statement. My company wants to pay the liability (...)

Open Orphan has secured ethical approval for a trial that involves deliberately infecting people with the Covid virus.

Open Orphan, the Irish clinical trials group, has secured ethical approval for a trial that involves deliberately infecting people with Covid in a con(...)

 Pep Guardiola gives instructions to  Phil Foden. The Manchester City boss will be hoping to see his side strengthen their grip at the top of the league with victory at Everton.   Photograph: Rui/Vieira/AFP/Getty

Pep Guardiola believes soccer will experience a rise in Covid cases again as a result of next month’s international break but has indicated he will n(...)

When you switch mortgages, there are two considerations: lower monthly payments and what you save overall in interest payments over the remaining life of your loan. Illustration: iStock

I wonder if you could give me a little advice? We currently have a variable mortgage of 2.95 per cent with AIB with a balance of €187,610 remaining ov(...)

This is not to say housing here is affordable or slowly becoming affordable. It’s patently not. Photograph: iStock

The medium-term trend for house prices is not up, it’s down, and we should be wary of estate agents telling us otherwise. We had our fill of self-serv(...)

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