Workers at  AstraZeneca’s  Macclesfield site in England.  Shares in the British drug giant suffered their largest ever fall as it announced a big setback, with a much-awaited trial of a new lung cancer drug failing to show the benefits for which the company had hoped. Photograph: Phil Noble/Reuters

Shares in AstraZeneca were on track to suffer their worst ever fall after the Anglo-Swedish pharmaceutical company suffered a big setback with a much-(...)