Monday motivation: Britain’s chief negotiator David Frost (centre) removes his face mask to talk to the media as he arrives for Brexit talks in Brussels. Photograph: Francisco Seco/AP

Image of the week: Frosty the Brexit man Britain’s chief Brexit negotiator David Frost – known in Downing Street as “Frosty” – had a busy week in Bru(...)

John Prine in Nashville in 2016. Photograph: Kyle Dean Reinford/The New York Times

Born: October 10th, 1946 Died: April 7th, 2020 John Prine, who has died aged 73 due to complications of Covid-19, was a highly influential American s(...)

Bari Brooks, who received four chemotherapy treatments, six weeks of radiation and five years of hormone-blocking therapy for a study on breast cancer, in White House, Tennessee. Photograph: William DeShazer/The New York Times

Many women with early-stage breast cancer who would receive chemotherapy under current standards do not actually need it, according to a major interna(...)