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Gilead employs more than 500 staff in Ireland, many working at its Cork plant, where it manufactures drugs for the treatment of HIV and hepatitis

The US is suing drugmaker Gilead Sciences for infringing government patents for the use of two of its flagship drugs to prevent HIV, saying the compan(...)

Traders work on the floor of the New York Stock Exchange. Global markets are reacting positivity to perceived improvements in world economic outlooks. Photograph: Epa/Justin Lane

European shares rose for a fifth straight session on Thursday to hit fresh four year highs as investors cheered signs of progress in US-China trade ta(...)

French president Emmanuel Macron: ‘You have partners together in the same part of the world, and you have no co-ordination whatsoever of strategic decision-making between the United States and its Nato allies – none.’  Photograph:   Ludovic Marin/Reuters

French president Emmanuel Macron has opened a rift with Germany and other Nato allies weeks ahead of a vital summit after he warned that the transatla(...)

The UK’s shadow chancellor, John McDonnell, speaking in Liverpool on Thursday.   “It means that the centre of political gravity is shifting away from London. It’s coming back home to the north.” Photograph:  Richard Martin-Roberts/Getty Images

John McDonnell has announced a radical Labour plan to commit £400 billion (€460 billion) of investment to what he called the twin crises of the climat(...)

‘Technology continues to disrupt business models and digital has changed everything – the legal sector is not immune,’ said Tom Connor, head of the new digital services group. Photograph: iStock

Irish law firm Matheson is turning to technology to cement its foothold in the legal services market, creating a new digital services group with exper(...)

Visitors to the island are taken on a guided tour through its 1,300-year history.

It may well once have been about as attractive a destination as Van Diemen’s Land or the Bastille but the former prison of Spike Island has undergone (...)

Marks & Spencer ended marginally lower after jumping nearly 8 per cent earlier in the session. The chain reported a plunge in first-half earnings but like-for-like sales growth in its food business. Photograph: Reuters

European stocks scaled a fresh four-year peak on Wednesday driven by a surge in shares of consumer-focused companies that helped offset declines in au(...)

Alun Cairns: “This is a very sensitive matter and in the light of continued speculation, I write to tender my resignation as Secretary of State,” he said in a letter to Boris Johnson. Photograph:  Tolga Akmen/AFP via Getty Images

A cabinet minister has resigned on the first official day of the UK election campaign over allegations he knew a Conservative candidate for the Welsh (...)

 Global markets are reacting positively to perceived improvements in world economic outlooks, particularly an easing of tension on US/China trade. Photograph: Justin Lane/EPA

European shares hit four-year highs on Tuesday, edging closer to record levels, driven by a rally in energy and commodity-linked stocks as US-China tr(...)

Leader of Liberal Democratic Party Jo Swinson. Photograph:  Hollie Adams/EPA

The Liberal Democrats will not help Labour’s Jeremy Corbyn become British prime minister after next month’s election, leader Jo Swinson said on Tuesda(...)

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