Today
Aston Villa (6) v Sunderland (7)
Gareth Southgate will end his six-match absence from the Premiership after being sidelined by an Achilles tendon injury.
Niall Quinn has recovered from a knee injury that forced him out of the Republic of Ireland's midweek game with Greece.
Last season: No corresponding fixture
Last five league matches: Aston Villa W W W W D, Sunderland W W L W L
Top scorers: Dion Dublin 14; Kevin Phillips 29
Match odds: H 4-6 A 10-3 D 12-5
Referee: A D'Urso (Billericay)
Chelsea (5) v Liverpool (2)
Chelsea boss Gianluca Vialli has a number of defensive injury problems with full back Albert Ferrer definitely ruled out and centre back Marcel Desailly doubtful. Mario Melchiot will probably continue to deputise at right back for Ferrer.
Liverpool are banking on Stephane Henchoz's recovery from a groin injury. The Swiss defender has barely trained this week, but boss Gerard Houllier is confident that Henchoz will make the trip to London.
Last season: Chelsea 2 Liverpool 1, Liverpool 1 Chelsea 1
Last five league matches: Chelsea W W L D L, Liverpool W W W W D
Top scorers: Tore Andre Flo 19; Michael Owen 13
Match odds: H 7-5 A 6-4 D 9-4
Referee: G Barber (Tring)
Everton (9) v Arsenal (3)
Fit-again Francis Jeffers is hoping for a first Premiership start since January 24th. Everton have injury problems with defender Richard Gough (calf) and Joe-Max Moore (knee).
Thierry Henry is out for Arsenal as he nurses his hamstring injury. Dennis Bergkamp and Kanu will be Arsenal's strikepartnership. Skipper Tony Adams has been passed fit, as has Patrick Vieira.
Last season: Everton 0 Arsenal 2, Arsenal 1 Everton 0
Last five league matches: Everton L W D W D, Arsenal W W W W W
Top scorers: Kevin Campbell 12; Thierry Henry 24
Match odds: H 12-5 A 10-11 D 9-4
Referee: D Gallagher (Banbury)
Newcastle (12) v Coventry (14)
Peruvian midfielder Nolberto Solano has joined Newcastle's casualty list after damaging an ankle on international duty. Alessandro Pistone is back just 12 weeks after breaking a leg and will definitely play and Georgian Temuri Ketsbaia has recovered from a knee injury.
Coventry will make at least one change from the side beaten by West Ham, as Barry Quinn damaged his ankle ligaments playing for the Republic of Ireland in midweek.
Last season: Newcastle 4 Coventry 1, Coventry 1 Newcastle 5
Last five league matches: Newcastle L W L L D, Coventry L L L W L
Top scorers: Alan Shearer 32; Robbie Keane 18
Match odds: H 4-9 A 5-1 D 11-4
Referee: P Jones (Loughborough)
Southampton (15) v Leicester (11)
Leading scorer Marian Pahars is poised to return after missing Monday's 2-0 defeat at Derby.
Darren Eadie is set to return for Leicester after being sidelined since spraining an ankle in the 3-0 defeat at Derby earlier this month.
Last season: Southampton 2 Leicester 1, Leicester 2 Southampton 0
Last five league matches: Southampton L W W L L; Leicester L D W L D
Top scorers: Marian Pahars 13; Tony Cottee 10
Match odds: H 6-5 A 7-4 D 9-4
Referee: M Reed (Birmingham)
Tottenham (10) v Derby (16)
Spurs have worries over the left back position. Mauricio Taricco missed the last game with a stomach injury and Luke Young is struggling with a hip problem.
Belgium striker Branko Strupar is doubtful for Derby after picking up a hip injury against Southampton.
Last season: Tottenham 1 Derby 1, Derby 0 Tottenham 1
Last five league matches: Tottenham L L L W W; Derby W D L D W
Top scorers: Steffen Iversen 18; Branko Strupar 16
Match odds: H 8-11 A 3-1 D 12-5
Referee: N Barry (Scunthorpe)
Watford (20) v Man Utd (1)
Tommy Mooney is back in the squad for the first time since September after finally recovering from a knee injury. The versatile star of last year's promotion season came through a reserve game at Derby in midweek.
Ronny Johnsen looks certain to figure as he continues his comeback from a double knee operation. Andy Cole is expected to return after he sat out the Chelsea match on Easter Monday.
Last season: No corresponding fixture
Last five league matches: Watford D L D L L; Man Utd W W W W W
Top scorers: Heidar Helguson & Allan Smart 5; Dwight Yorke 23
Match odds: H 7-1 A 1-3 D 3-1
Referee: S Lodge (Barnsley)
West Ham (8) v Middlesbrough (13)
Goalkeeper Ian Feuer is fit to face Middlesbrough. Steve Lomas (toe) and Scott Minto (cartilage) will not play again this season. Marc Keller replaces Minto.
Middlesbrough defender Christian Ziege will undergo a late fitness test on a groin injury. Colombian striker Hamilton Ricard will be assessed after meeting up with his teammates in London after making the long journey back from a World Cup qualifier in Bolivia.
Last season: West Ham 4 Middlesbrough 0, Middlesbrough 1 West Ham 0
Last five league matches: West Ham W L W W W, Middlesbrough W W L L D
Top scorers: Paolo Di Canio & Paulo Wanchope 16; Hamilton Ricard 14
Match odds: H 4-6 A 7-2 D 9-4
Referee: B Knight (Orpington)
Sunday
Bradford (18) v Wimbledon (17)
Bradford manager Paul Jewell will choose from the same squad for Sunday's crunch relegation battle with Wimbledon who were on duty for Monday's 1-0 win at Sunderland.
John Hartson is ready to return for Wimbledon. He has been out injured since December but returned to training this week. Ben Thatcher is also striving to be fit after a nagging ankle injury.
Last season: No Corresponding fixture
Last five league matches: Bradford L L L D W; Wimbledon L L L L L
Top scorers: Dean Windass 9; Carl Cort 17
Match odds: H Evens A 11-5 D 11-5
Referee: J Winter (Stockton-on-Tees)
Sheff Wed (19) v Leeds (4)
Sheffield Wednesday manager Peter Shreeves has no fresh injury worries to contend with. Shreeves will go with the same squad which faced Sunderland in last week's 2-0 home defeat.
Leeds midfielder Lee Bowyer and left back Ian Harte are both suspended.
Last season: Sheff Wed 0 Leeds 2, Leeds 2 Sheff Wed 1
Last five league matches: Sheff Wed L L W W L; Leeds L L L L D
Top scorers: Niclas Alexandersson & Gilles De Bilde 9; Michael Bridges 18
Match odds: H 7-4 A 11-10 D 5-2
Referee: R Harris (Oxford)
Match odds supplied courtesy of William Hill
