Saturday
Aston Villa (10) v West HAM (14)
Juan Pablo Angel is the only fitness concern for Villa, with the £9.5 million striker missing the last two games after returning from international duty with Colombia suffering from a knee injury. If he is passed fit, then the best he can seemingly hope for is a place on the bench.
Svetoslav Todorov could make his first start for West Ham, with boss Harry Redknapp looking for goals as his team bids to end a run of five successive defeats and may turn to the Bulgarian international striker for the answer.
Last season: West Ham 1 Aston Villa 1, Aston Villa 2 West Ham 2.
Last five league matches: Aston Villa D W D W W, West Ham W L L L L.
Top Scorers: Julian Joachim (Aston Villa) 8; Frederic Kanoute (West Ham) 11.
Match Odds: H 4/5; A 11/4; D 23/10.
Referee: R Harris (Oxford).
Derby (16) v Chelsea (7)
Goalkeeper Mart Poom returns to the Derby side for the Premiership clash against Chelsea as Andy Oakes is sidelined with a knee injury. Defenders Taribo West and Chris Riggott are also available again after missing the defeat by Coventry with flu and a groin injury. Scotland midfielder Craig Burley is ruled out with a hamstring injury.
Defender Frank Leboeuf (groin) is still out so Chelsea retain the 16-man squad involved in last weekend's 2-1 win against Middlesbrough, with Albert Ferrer and Gus Poyet also included in the travelling party. Defender Mario Melchiot is hopeful of playing despite sustaining an ankle injury against Boro.
Last season: Chelsea 4 Derby 0, Derby 3 Chelsea 1.
Last five league matches: Derby D W W D L, Chelsea D D W L W.
Top Scorers: Malcolm Christie (Derby) 10; Jimmy Floyd Hasselbaink (Chelsea) 22.
Match Odds: H 5/4; A 6/4; D 21/10.
Referee: S Lodge (Barnsley).
Leeds Utd (4) v Southampton (11)
With Lucas Radebe ruled out for the rest of the season, Rio Ferdinand will again skipper Leeds, with Dominic Matteo partnering him at the heart of the defence. Robbie Keane is also available after missing Wednesday's Champions League quarter-final first leg 3-0 victory over Deportivo La Coruna due to his ineligibility.
Southampton are set to welcome back skipper Jason Dodd following a knee injury which seen him sidelined since February. Striker Kevin Davies is also in contention for a recall after recovering from a shoulder problem which kept him out of Monday's home defeat to Ipswich, but Moroccan midfielder Hassan Kachloul (calf) is still a major doubt.
Last season: Leeds Utd 1 Southampton 0, Southampton 0 Leeds Utd 3.
Last five league matches: Leeds D W D W W, Southampton W W W W L.
Top Scorers: Mark Viduka (Leeds) 20; James Beattie (Southampton) 12.
Match Odds: H 4/9; A 11/2; D 13/5.
Referee: J Winter (Stockton-on-Tees).
Leicester (9) v Coventry (19)
Dean Sturridge (hamstring) is out for Leicester, but leading scorer Muzzy Izzet could return after a calf injury, but Leicester manager Peter Taylor will not risk the 11-goal midfielder if he is less than fully fit. However, Robbie Savage, Frank Sinclair, Matthew Jones and Darren Eadie are still all ruled out.
Coventry have no injury worries and manager Gordon Strachan is likely to field the team which beat Derby County 2-0 last weekend.
Last season: Coventry 0 Leicester 1, Leicester 1 Coventry 0.
Last five league matches: Leicester W W L L L, Coventry D D D L W.
Top Scorers: Muzzy Izzet (Leicester) 11; John Hartson (Coventry) 15.
Match Odds: H 8/11; A 3/1; D 12/5.
Referee: G Barber (Tring).
Sunday
Everton (15) v Man City (18)
Kevin Campbell and Richard Gough return to the Everton squad after recovering from calf injuries. Francis Jeffers is also included despite being troubled by an ankle injury while Mark Pembridge remains doubtful with a calf problem.
Paulo Wanchope is expected to make his first appearance since the end of January to help City's relegation battle. Steve Howey will have a late fitness test on his thigh strain, but should be available, and City's only definite absentees are the injured Kevin Horlock and Paul Ritchie.
Last season: No corresponding fixture.
Last five league matches: Everton W L D L W, Man City L W L D L.
Top Scorers: Kevin Campbell, Francis Jeffers (Everton) 8; Paulo Wanchope (Man City) 14.
Match Odds: H 4/5; A 11/4; D 23/10.
Referee: D Elleray (Harrow-on-the-Hill).