Taliban Ambassador to Pakistan Abdul Salam Zaeef has said no harm had come to Osama bin Laden or Taliban leader Mullah Mohammad Omar after four days of US strikes.
However officials said the civilian death toll was rising from the attacks, which the United States has said were directed at such military targets as defence systems, airfields and guerrilla training camps.
At least 76 people have been killed and over 100 injured across the country in the raids so far, according to the Afghan Islamic Press and officials.
Six civilians, including an elderly woman and her two daughters were killed in strikes late last night on the outskirts of the eastern city of Jalalabad, a town surrounded by several of bin Laden's training camps.
Two young women and two young girls were injured by shrapnel from a US bomb dropped in a pre-dawn air raid on the eastern outskirts of Kabul, witnesses said.
The bomb hit a wall of a disused fort in Dehyaya village about 15 km to the east of Kabul, wounding two little girls, their mother and a nomad woman living nearby.
"We were about to get up for morning prayers when the bomb landed. My two daughters and wife received injuries from flying glass and shrapnel," said the father of the family.
The only other victims were four sheep belonging to a nomad family that had camped near the wall, which had partly collapsed in the blast.
"America's war is with Islam and targeting civilians like us is a clear example of that," said one villager.