Variant CJD – originally found among cannibals in Papua New Guinea – is caused by the same prion strain that caused the BSE epidemic in cattle in the mid-1990s in Britain and Ireland. Above, research is carried out into Creutzfeldt-Jakob disease.  Photograph: Raphael Gaillarde/Gamma-Rapho via Getty Images

Blood and organ donations could represent a major source of the deadly Creutzfeldt Jakob brain disease because infected donations from carriers cannot(...)

Andrew Hughes, whose historical novel The Convictions of John Delahunt focuses on an informer who ends up being hanged, and is based on real 19th-century people. Photograph: Alan Betson

Who knows what historical horrors lurk behind our elegant Georgian facades? Andrew Hughes, for one. An archivist by training, his social history of Fi(...)

Guardian Media Group Plc returned to a full-year profit as a 29 per cent increase in digital revenue helped offset declining newspaper circulation

Guardian Media Group Plc, which owns the UK’s Guardian and Observer newspapers, returned to a full-year profit as a 29 per cent increase in digital re(...)

Kevin Barry has won the International Impac Dublin Literary Award, one of the world’s richest literary prizes, for his novel City of Bohane. Photograph: Cyril Byrne/The Irish Times

Kevin Barry has won the International Impac Dublin Literary Award, one of the world’s richest literary prizes, for his novel City of Bohane. The winne(...)

Hisham Matar’s superb novel Anatomy of a Disappearance   failed to make it past the Impac longlist.  Photograph: Brenda Fitzsimons

Ireland’s Kevin Barry, an artist of daring and linguistic panache, has been declared the victor. This is the third Irish Impac win to date, and at suc(...)