Prof Stephen O’Rahilly, who discovered the obesity gene affecting children, is head of  clinical biochemistry and director of the Institute of Metabolic Science at the University of Cambridge. Photograph: Phil Mynott

Stephen O’Rahilly struggles with his weight. “I have a very powerful appetite, I eat too much. I would find it impossible to skip lunch,” the Cambr(...)

The ninth-century Tatev Monastry, an icon of the ancient Armenian Apostolic Church, reached by the world’s longest aerial tramway. Photograph: Hayk Melkonyan

“Whole generations have been lost. We are left without children and it means we are left without a future.” I remember those words vividly. They were (...)

An al Nusra front fighter carries his brigade’s flag in Idlib city, after they took control of the area in March. Photograph: Ammar Abdallah/Reuters

A Columbus, Ohio, man who trained with Islamic militants in Syria has been arrested and charged with supporting terrorism and making false statements.(...)

Ingredients and convenience food group Kerry climbed 1.67 per cent to close at €67.50

European stocks declined yesterday, breaking a five-day advance, as banks slid. DUBLIN Permanent TSB’s announcement that it is planning to seek a pri(...)

Nicholas Slatten (left), a former Army sniper from Tennessee, was sentenced to life in prison; Dustin Heard, also of Tennessee and  Evan Liberty of New Hampshire were both sentenced to  30 years. Photograph: Reuters

One former Blackwater security contractor received a life sentence on Monday and three others received 30-year sentences for killing unarmed Iraqi ci(...)

US senator Marco Rubio has announced that he is to seek the Republican nomination in the 2016 presidential election.  Photograph: Jim Lo Scalzo/EPA

US senator Marco Rubio of Florida told top donors that he will run for the White House because he is “uniquely qualified” to represent the Republican (...)

A Lamborghini that was part of an exotic car racing attraction at Walt Disney World crashed into a guardrail, killing a passenger and injuring the driver, police said. Photograph: WFTV via AP

A Lamborghini that was part of an exotic car racing attraction at Walt Disney World crashed, killing a passenger and injuring the driver.The Florida H(...)

Hillary Clinton announced her campaign for the US presidency in a video posted to hillaryclinton.com.   Photograph: Hillary For America via AP

Hillary Rodham Clinton has officially launched her second attempt to become the first female US president, firing the starting gun on the 2016 pres(...)

Hillary Clinton: I’m getting ready to do something too . . . I’m running for president. Photograph: Pete Marovich/Bloomberg 0:52

Hillary Rodham Clinton on Sunday officially launched another attempt to become the first female president, ending years of speculation and firing the (...)

Former first lady Hillary Clinton is viewed as the Democrats’ best bet of retaining the White House. Photograph: Andrew Gombert/EPA

Hillary Clinton will end months of speculation on Sunday when she announces she is running to become the first female president of the United States,(...)