Trade representatives  during the closing press conference after an agreement was reachef by 12 Trans-Pacific Partnership (TPP) member countries. Photograph: EPA/ERIK S. LESSER

Some of the biggest trading entities in the region have been circling each other for the past few weeks after a US-led trade deal was struck between 1(...)

Breast cancer cell. The new genomic testing may also indicate whether or not the treated cancer is likely to recur. Photograph: Getty Images

The number of women diagnosed with breast cancer who undergo unnecessary chemotherapy could be dramatically reduced following results from medical fin(...)

Pupils of Mount Temple Take part in red tshirt day. Photograph: Stephen McCullagh

An initiative started by a Dublin man in response to the image of a three-year-old drowned refugee is being replicated around the world. Bernard Dunl(...)

The Federal Reserve: the IMF urged it to wait until next year to raise rates for the first time in almost a decade

The International Monetary Fund has warned that emerging economies and bond markets need to prepare for an increase in corporate failures if and when (...)

Hedge fund increases stake in Alliance Trust.

The activist hedge fund Elliott that forced change at Alliance Trust this year has increased its stake to more than 14 per cent, adding to pressure on(...)

Policemen investigate the area around a murder scene in Kumagaya, Saitama  where six people were found stabbed to death. Photograph: Getty

The brother of a notorious Peruvian mass murderer dubbed the “apostle of death” has been arrested in Japan over suspicions he killed six people himsel(...)

Killybegs mackerel skipper Martin Howley

Tributes have been paid to pioneering mackerel skipper, Donegal-based businessman and fishing industry leader Martin Howley who has died after a short(...)

Kidnap victims  disembark from an army helicopter in Junin, Peru after being rescued. Photograph: Luis Enrique Saldana/EPA

A Peruvian military operation in the Andes has secured the release of more than a dozen adults who were kidnapped by the Shining Path rebel group up t(...)

Members of the Mashco Piro tribe in Manu National Park. The Peruvian state will try to make contact with the isolated Amazonian tribe following an arrow attack on a  village in May. Photograph: Reuters/Jean-Paul Van Belle

Peru will make contact for the first time with an Amazonian tribe that largely lives isolated in the jungle, part of a bid to ease tensions with near(...)

In one of the most bizarre twists in America’s war on terrorism, the CIA assigned veteran operations officer Harold James “Jim” Nicholson to run a cou(...)