Japan’s benchmark Nikkei 225 Stock Average surged 7.7 per cent, gaining more than 1,300 points, as sentiment was bolstered by  rallies on Wall Street and optimism on China economy. Photograph: . Franck Robichon/EPA

Global markets continued to respond to positive developments in China. In the US, stocks struggled to add to their second best rally of the year, even(...)

A screen shows the final tally for the Dow Jones Industrial Average on the floor of the New York Stock Exchange, yesterday.  Photograph: Brendan McDermid/Reuters

World stock markets tumbled towards their worst week of the year yesterday and commodities got another kicking, as more alarming data from China sent(...)

‘Nominating a legacy contact is harder than it looks, not least because of its brutal implication. The simple fact that it exists at all is a stark reminder that life is finite. Which is such a bummer. Facebook isn’t the place to go to learn that you’re going to die.’ Photograph: Getty Images

As a man in my mid-30s in the year 2015, I spend the bulk of my life diligently and repeatedly carrying out one simple task – ignoring the prospect of(...)

GlaxoSmithKline moved to reclaim its prowess as a research powerhouse on Wednesday by flagging up dozens of new drugs and vaccines in development, as(...)

Modern 191-bedroom hotel in Cork has extensive conference and leisure facilities. Photograph: Tony Healy

The landmark four-star Clarion Hotel on Cork’s Lapps Quay is on the market at €30 million through joint agents JLL and Savills. If it sells at its gui(...)

GSK announced it is recruiting 50 permanent and temporary employees at its manufacturing site in Sligo in 2015

Analytics company Numerix has announced it will create 30 jobs over three years at its new office in Dublin, while GlaxoSmithKline (GSK) will recruit (...)

Perrigo chief executive and chairman Joe Papa.  Photograph: Brenda Fitzsimons / The Irish Times

Perrigo, the Irish specialist in over the counter drugs, has agreed to buy a portfolio of products from GlaxoSmithKline. GSK’s consumer healthcare div(...)

GlaxoSmithKline  says it has built up a valuable intellectual property over the last 15 years in the use of “the unique and distinctive colour purple” on its Seretide inhaler. Photograph: Getty Images

A major pharmaceutical company which alleges trademark infringement has been refused an injunction preventing the roll-out by a rival of an inhaler fo(...)

Audi R8: the company’s results are out today.   Photograph: Ian West/PA Wire

TODAY Results: Audi; First Bancorp; Perrigo. Indicators: US factory orders (March); Chinese HSBC manufacturing PMI (April); Euro zone Markit manufa(...)

Mothers wait  with their children  in Bagamoyo, Tanzania, during tests for a  vaccine against malaria. Researchers have said that final clinical trials of a possible world-first licensed vaccine for the disease suggest the jab has the ‘potential to prevent millions of cases’.  Photograph:  Tony Karumba/AFP/Getty Images

Final clinical trials of a possible world-first licensed vaccine for malaria suggest the jab has the “potential to prevent millions of cases”, researc(...)