Dublin-based Shire was itself the target of a failed $50 billion takeover attempt by AbbVie last year.

Drugmaker Shire said on Tuesday it was seeking to buy Baxalta, a company spun-off by Baxter International last month, for $30 billion (€27.35 billion)(...)

Donald Bullock, a former testing coordinator with Atlanta Public Schools, is led to a holding cell after the verdict that found him and 10 others guilty of racketeering. Photograph: Kent D Johnson/Pool via The New York Times)

In what has been described as the largest cheating scandal in America’s history, a jury on Wednesday convicted 11 educators for their roles in a stand(...)

Ireland celebrate their World Cup win over the tournament favourites New Zealand. Photograph: Dan Sheridan/Inpho 1:31

Ireland 17 New Zealand 14Come here, ever hear the one about the Irish men trying and failing to beat New Zealand in test rugby for over a century befo(...)

The 10-month investigation into the three billion yuan (€350 million) worth of suspicious travel and meeting expenses and trade in sexual favours at GlaxoSmithKline is the highest-profile international case since the Chinese government launched its massive crackdown on corruption. Photograph: AP

Chinese police have charged the British former head of drugmaker GlaxoSmithKline’s China business and other senior colleagues with corruption, after a(...)

Chief Constable Matt Baggott: writing to Norman Baxter requesting him to clarify and expand on claims  he made. Photograph: Colm Lenaghan/Pacemaker

PSNI Chief Constable Matt Baggott has attempted to kick to touch serious allegations made by former senior police offic(...)

 Ireland’s Dan Leavy is forced off with a shoulder injury against England at Franklin’s Gardens.  Chris Vaughan/Inpho

There was some mixed news for Ireland coach Mike Ruddock ahead of Friday night’s Under 20 international against Italy at Dubarry Park (7.05). (...)

 Ireland’s Larissa Muldoon celebrates scoring her try against England in the  Women’s Six Nations match at Twickenham on Saturday. Photograph: James Crombie/Inpho

England 17 Ireland 10: There are moments in a game that resonate. The sight of Ni(...)

Pfizer is cutting a further 150 jobs at its Newbridge plant in Co Kildare

Confirmation by Pfizer that it is cutting a further 150 jobs at its Newbridge plant triggered widespread calls for action to address what Fianna Fáil’(...)

St Vincent’s Ciaran Dorney, Eamon Fennell and Shane Byrne celebrate winning the Dublin  SeniorFootball Championship final replay. Photograph: Morgan Treacy/Inpho

DUBLIN SFC FINAL REPLAY: St Vincent’s 1-9 Ballymun Kickhams 1-8Heffo would have been delighted. In the year St Vincent’s lost the man who made them wh(...)

Andrew Witty, GlaxoSmithKline Plc chief executive officer: he will hope his investors are concentrating on the numbers when he unveils the FTSE 100 giant’s second-quarter financial results at midday today.

GlaxoSmithKline chief executive Sir Andrew Witty will hope his investors are concentrating on the numbers when he unveils the FTSE 100 giant’s second-(...)