Pfizer and Allergan would have to pay the other party just $400 million if either were to pull out of their $160 billion deal due to a change in th(...)

Jack Lew: The latest efforts by the US treasury secretary   to clamp down on inversions are irrelevant for the Pfizer deal, which meets previous thresholds laid down by his department for inversions.   Photograph: Simon Dawson/Bloomberg

The spluttering from Washington can be heard clearly across the Atlantic. The trouble is that the more it squares up on inversions, the more the Unite(...)

Pfizer’s plant at Newbridge, Co Kildare Photograph: Reuters

Pfizer is in advanced talks to buy Irish-based Allergan for as much as $380 (€353) per share, valuing the Botox maker at as much as $150 billion - if (...)

Pfizer is in negotiations with Dublin-based Allergan about buying the group in what would be the biggest ever “tax inversion” — allowing the company to report much lower tax costs by moving its domicile to Ireland. (Photograph: Scott Eisen/Bloomberg)

The chief executive of Allergan, in talks about selling itself to Pfizer to form the world’s largest drugmaker, has cautioned that any attempt by the(...)

AstraZeneca chief executive Pascal Soriot: ‘This acquisition complements our strategic focus on cardiovascular and metabolic disease.’ Photograph: Simon Dawson/Bloomberg

Britain’s AstraZeneca has agreed to buy US biotech company ZS Pharma for $2.7 billion, pipping Swiss firm Actelion to the prize in the latest bout of (...)

Audi: results out today.   Photograph: Akio Kon/Bloomberg
For your diary

TODAY Results: Aramark; Audi; Avis Budget; Estee Lauder; Inmarsat; Ryanair; PostNL; Visa. Indicators: Irish Investec manufacturing PMI; Irish consumer(...)

A man walks past Pfizer’s world headquarters in New York. The group is reportedly holding talks with Allergan on a possible merger

Drug companies Pfizer and Allergan have confirmed that they were engaged in “friendly” talks about a possible megamerger which would make Ireland home(...)

Wolseley led the drop, falling 12.5 per cent, after it forecast North American industrial markets will be challenging, and the UK heating industry will remain competitive. Photograph: Anna Gowthorpe/PA Wire

Financial markets remained on edge after a rout Monday, as a rally in US stocks faded while gauges of European and emerging-market equities retreated.(...)

New cancer drug cocktails set to reach the market in the next few years will test the limits of premium pricing for life-saving medicines, forcing com(...)

US doctors and teaching hospitals got $6.49 billion from drug and medical-device makers in 2014, according to new government data .

US doctors and teaching hospitals got $6.49 billion from drug and medical-device makers in 2014, according to new government data on the financial lin(...)