Shire  “trying to do the right thing” by running the pharmaceuticals company as efficiently as possible, says chief executive Flemming Ornskov

Shire’s chief executive has defended the company’s tax arrangements after being identified as one of the beneficiaries of alleged “industrial scale” (...)

Shire acting chief financial officer Jeff Poulton said the company had obtained advice that the break fee should not be taxable in Ireland. Photograph: The Irish Times

Drug giant Shire is facing a potential tax bill of up to €480 million as Irish Revenue officials examine the fallout from a collapsed takeover of the (...)

One of the two blocks at Woodford Business Park in Santry, Dublin 17 for which the freehold interest is up for sale

A high-quality office investment with strong opportunities to enhance its value in the vibrant office letting market goes on the market today at Woo(...)

Express Scripts, which will no longer offer Harvoni, manages pharmacy benefits for about 85 million people in the US

Gilead Sciences may finally be forced to offer a lower price for its $94,500 hepatitis C drug. The biotechnology company could have no choice but to n(...)

An office worker watching the FTSE 100, which slumped by another 2 per cent today as fears over the global economy triggered another bleak session for volatile stock markets. Photograph:  PA Wire

US stocks recovered from early losses as St. Louis Federal Reserve Bank President James Bullard said policy makers should consider delaying the end of(...)

The very Shire executives who baulked at the original acquisition proposal are demanding Abbvie follow through on its takeover while Abbvie is widely expected to withdraw a recommendation to its own shareholders to back the deal when its board meets on Monday.  Photograph: Aidan Crawley/Bloomberg

Cantillon: US biopharmaceuticals group Abbvie is in danger of proving the Obama administration and its truculent Congress right. Its increasing reluct(...)

Dublin-headquartered Shire stands to be paid a break-up fee of about $1.64 billion if Abbvie’s shareholders vote against the deal

US pharmaceutical company AbbVie has recommended that shareholders vote against its $55 billion takeover of Dublin-headquartered Shire in the wake of(...)

 Enda Kenny said Ireland was a place where “real companies employ very significant numbers of people”.

Ireland is “not a brass-plate location” for companies moving their residency for tax purposes and the Government has told the US it has never been a(...)

US medical device maker Medtronic’s plan to move its tax base to Ireland may be in doubt under rules announced by the Obama administration yesterday.

Medtronic, the Minnesota-based medical device maker that’s planning to take an Irish tax address, may become one of the biggest losers under rules ann(...)

Tim Hortons employees prepare coffee before the company’s annual general meeting in Toronto. Burger King Worldwide is in talks to acquire Tim Hortons. The combined company would be headquartered in Canada, where Tim Hortons is based and taxes are generally lower than in the US. Photograph: Peter Jones/Reuters
Inversion express slow to crawl

President Barack Obama’s full- throated denunciation of overseas mergers that lower US companies’ taxes is throwing cold water on potential deals. On (...)