The ReActiv-8 device has begun a new trial aimed at securing a premarket approval for the US.

Company has already begun commercialising back pain device in Europe

Pfizer, Novartis, Roche, AbbVie, Bayer and Merck are among the 47 pharma companies analysed in the report compiled by PatientView. Photograph: Getty Images

Drug companies rank lower overall for innovation and reputation in worldwide report

Oneview chief executive  James Fitter and  founder Mark McCloskey: “Innovative healthcare leaders like LG Health select Oneview for its inherent ability to improve the patient experience.” Photograph: Peter Moloney

Irish group will provide interactive patient care software in Lancaster General Hospital

Revenue’s clampdown is targetting a smallish number of people who over many years have been fairly blatantly gaming the system. Photograph: Gareth Fuller/PA Wire

Q&A: Dominic Coyle answers your personal finance questions

Members of staff leaving the Coty beauty products manufacturing plant in Nenagh after hearing that the factory is going to close with the loss of 200 jobs. Photograph: Brian Gavin / Press 22

First staff will be let go by October with final shutdown scheduled by end of 2018

Coty’s Nenagh plant, which manufactures Max Factor products, had been in competition with a plant in Kent for the business.

Business to transfer to English plant months after takeover of Procter & Gamble unit

How has your Fyffes investment grown? Photograph: Getty Images/iStockphoto

Q&A: Dominic Coyle answers your personal finance questions

Nabawi Mosque in Medina, Saudi Arabia: moving back to Ireland after 17 years in the country. Photograph: iStock

Q&A: Dominic Coyle answers your personal finance questions

Oneview chief executive James Fitter with founder Mark McCloskey. Photograph: Peter Moloney

Australian-listed Irish group reports strong pipeline for interactive patient care solution

Amarin chief executive John Thero. Photograph: Cyril Byrne / The Irish Times

Irish biotech’s drug used to treat US patients with high levels of blood fats

It is likely there will be a  reduction in federal funding for renewable energy and sustainable development projects in the US under a Trump administration. Photograph: Nick Ansell/PA Wire

Pension funds could fund sustainable projects dropped by climate-sceptic president

The Boston Scientific plant in Galway. Photograph: Joe O’Shaughnessy

Move follows reports of problems with locking mechanism in valve replacement products

Revenue commissioner Liam Irwin

Declarations before May 1st mean reduced penalties and chance to remain anonymous

Revenue is sending letters to more than 480,000 taxpayers warning them to disclose details of any assets held abroad before an April 30th deadline.

Almost 500,000 to get letters urging them to declare assets held abroad before deadline

Houses in London: the Irish Revenue will hold you liable for tax over the full period of ownership of the UK property even though the British are only concerned with gains since April 2015

Dominic Coyle answers readers’ questions

“I received a form, with instructions to pay a €35 release fee.” Photograph: Alan Betson

Why do I have to pay a charge if these documents belong to me?

Oneview chief executive James Fitter and founder Mark McCloskey. Photograph: Peter Moloney

Non-profit group Barnes Jewish Healthcare to install 2,000 Oneview medical devices

Self-building:  nothing in the Finance Act 2016 – which contains the rules governing the Help-to-Buy scheme –  expressly lays down how a deposit should be paid in relation to self-builds. Library photograph: iStock

Dominic Coyle answers readers’ questions

The bottom line is that if Revenue suspects you could not afford the costs of nursing homecare from your own resources, they will disallow any tax relief claim on bills they determine were effectively paid by your mother by virtue of money she has given you. Photograph: Bryan O’Brien

Q&A: Your personal finance questions answered

Paul Reid,  MD of Pfizer Pharmacy. Photograph: Alan Betson

The drug giant’s point man in Ireland talks about acquisitions, setbacks, prices and Trump

 Minister for Health Simon Harris and Health Enterprise Alliance president Sandra Gannon. Photograph: Maxwells

Simon Harris keen to increase use of cheaper versions of off-patent medicines

Arrival of biosimilars is expected to deliver savings of more than €100m over the four-year life of the agreement

Generics lobby says biosimilars are being blocked but pharma group disagrees

Bank of Ireland says it  will keep property deeds safely once a mortgage has been repaid until the deeds are requested by the customer. Photograph: Yui Mok/PA Wire

Q&A: Dominic Coyle answers your personal finance questions

Simon Harris: The Minister for Health has said his department is developing a national biosimilar policy. Photograph: Dara Mac Donaill

Arthritis drug Benepali barely sells while branded competitor dominates market

Medicine costs: a significant  portion of the €750 million in savings expected under a drug pricing deal between now and mid-2020 may not be delivered. Photograph: Getty

Low sales of ‘biosimilar’ arthritis medicine paves way for branded drugs to avoid 30% cut

Healthcare potential: the MSD facility in Swords, Co Dublin. Photograph: Brenda Fitzsimons

Pharmaceutical company’s trials over next three years will focus on cancer treatments

Oneview chief executive James Fitter and founder Mark McCloskey. Photograph: Peter Moloney

Hospital software group to help create platform to monitor impact of patient care plans

Mainstay Medical’s has announced the first sale of its ReActiv8 neurostimulator to treat chronic lower back pain  at a hospital in Koblenz, Germany

Iseq-listed medical device firm targets commercial growth and completion of US clinical trials

Help to buy? An estate agent’s shop window in Dublin. Photograph:   Brian Lawless/PA Wire

Q&A: Dominic Coyle answers your personal finance questions

Under the reformed measure passed in the Finance Act, the gifting of homes under the dwelling house relief is ended unless the person concerned is a family member so incapacitated that they cannot provide for themselves.

Q&A: Dominic Coyle answers your personal finance questions

For the purposes of  the Help to Buy scheme, the value of a self-build is the valuation put on the property project by the mortgage lender. Photographer: Jason Alden/Bloomberg

Q&A: Dominic Coyle answers your personal finance questions

MOF Technologies chief executive Paschal McCloskey: “Excelsa Ventures is a perfect fit for a company like us.”

MOF Technologies to quadruple research capacity and expand production lines

The rewritten section 86 importantly returns to dwelling house relief being permitted only in cases of inheritance

Q&A: Dominic Coyle answers your personal finance questions

Up to 50 workers recruited for Pfizer’s Ringaskiddy plant in Cork since 2014 have found themselves impacted by the ongoing dispute over pension entitlements. Photograph: Don Emmert/AFP/Getty Images

Staff at Ringaskiddy in dispute over pensions for new employees

In New York on Wednesday, Donald Trump told his first press conference as US president-elect: “We’ve got to get our drug industry back.” Photograph: Don Emmert/AFP/Getty Images

President-elect targets pharma and medtech sectors

Pfizer said the cost of funding non-contributory defined-benefit pension schemes in Ireland had risen by more than 1,000 per cent since 2009. Photograph: Dan Kitwood/PA Wire

Workers in Cork plants object to closure of non-contributory defined-benefit plans

US president-elect Donald Trump held his first news conference since his election on Wednesday.  Photograph: Don Emmert/AFP/Getty Images

President-elect says he will bring drug industry back to US and tackle high drug prices

 “The abuse of this scheme has been a concern of Revenue for years,” said TD Joan Collins. Photograph: Cyril Byrne

Perceived abuse of dwelling-house exemption to avoid paying tax has led to reform

Genomics Medicine Ireland will work with Abbvie to examine potential genetic triggers for a series of major chronic diseases in the areas of cancer, neurosciences and immunology. Photograph: Conor McCabe/GMI

Genomics Medicine Ireland is joining with Abbvie to develop drugs to fight cancer

Assuming the Fyffes takeover is approved, the payout to shareholders will be €2.25 per share.

Q&A: I bought Fyffes shares at IR£1.70 in 2000. What is my capital gains tax situation?

Consistent returns over the long term are most important to pension investors. Photograph: iStock

Average return of 5.8% despite Brexit shock and poor start to the year

NeRRe Therapeutics targets common conditions where there is currently unmet medical need using a pathway called neurokinin receptors. Photograph: Getty Images/iStockphoto

Investment by Fountain Healthcare Partners to also target treatment for chronic coughing

The purchase scheme offers first-time buyers the chance to get up to €20,000 to put against their deposit on a new home. Photograph: Rui Vieira/PA Wire

Numbers of first-time buyers signing up for home incentive set to rise in coming days

The scheme is available only to owner-occupiers, not to the investment or buy-to-let market, and applicants will need to live in the property for five years

Revenue scheme to help first-time buyers starts in 2017

Taoiseach Enda Kenny and Bruce Cozadd, chairman and chief executive of Jazz Pharmaceuticals. Photograph: Shane O’Neill/Fennells

Drug firm with Athlone manufacturing plant seen as second fastest-growing US share

Nationwide UK got confused over the status of Irish customers at its Nationwide UK (Ireland) operation

Q&A: Dominic Coyle answers your questions

Bausch & Lomb

Ballot on 9.5% three-year deal wins 80% support from workers at contact lens plant

You do not have to file a capital gains tax return if the gain  is under the exemption limit.

Q&A: Dominic Coyle answers your personal finance questions

Bausch + Lomb: A  dispute between management and Siptu workers had become increasingly intransigent, but a deal was hammered out  on Wednesday.

Siptu and management hammer out 9.5% pay rise as industrial action loomed

Nishi Ward, founder of Waste Systems (second left), Allen Martin, senior executive, Kernel Capital, William McCulla, Invest NI corporate finance director, and   Andy Palmer,  customer service manager, Bank of Ireland UK

Waste Systems has international market for equipment that segregates recyclables

Oneview Healthcare chief executive James Fitter and founder Mark McCloskey. The Dublin company is installing its software at St Louis Children’s Hospital in St Louis, Missouri. Photograph: Peter Moloney

Contract could see Irish medtech’s product rolled out across 15 hospitals in the midwest

Bausch & Lomb: workers at the Waterford plant took a 7 per cent  cut and 200 job reductions to ensure the survival of the plant. Photograph:   Mary Browne

Trade union and contact lens group to focus on talks aiming to resolve pay dispute

Once you have owned property anywhere, you are no longer classified as a first-time buyer for the purposes of the Irish Revenue. Photograph: Rui Vieira/PA Wire

Q&A: Irish national now back home wants to avail of first-time buyers’ initiative

“In effect, you are being penalised for your good track record. If you were currently renting and planning to buy, clearly the current rent would no longer be a cost to you and would be factored in.”

Q&A: Mortgage lenders leave customer in dark on whether savings on outgoings are factored in

Activity in the construction sector is expected to grow by 9 per cent annually between now and 2020. File photograph: Karim Jaafar/AFP/Getty Images

Irish companies are targeting skilled workers abroad to fill 112,000 vacancies

Management at the Bausch + Lomb contact lens and eyecare group plant has said it will implement measures that will involve job losses if agreement on pay and conditions is not reached by the end of next week

Company counters Siptu plan for work stoppages and overtime ban with warning that jobs will be cuts

U2 singer Bono with Nuritas founder and chief scientific officer Dr Nora Khaldi, The Edge and Nuritas chief executive Emmet Browne. Photograph: Kieran Harnett

U2 members put cash into product geared to tackle Type 2 diabetes

Allied Irish Banks: “A whole generation of Irish investors were consistently urged to invest in ‘blue-chip’ companies such as the leading banks”, including AIB. Photograph: Eric Luke

Q&A: Dominic Coyle answers your personal finance questions

Pfizer had expected cholesterol drug bococizumab to deliver sales of almost $1 billion a year. Photograph: Dan Kitwood/PA Wire

Project promising 1,250 construction roles pulled after failure of key cholesterol drug

Visitors  at the 186th RHA annual exhibition, includes painting, sculpture, photography, print, drawing and architectural models. Photograph: Cyril Byrne

Sales down 23% on 2015, but record attendence figures suggests revival of interest in art

Tysabri, the multiple sclerosis drug developed by Elan, may be sold again as Perrigo examines options.

CEO John Hendrickson says drug faces increased competition and potential for wider use has failed to materialise

Buying a house: the rules of the Help-toBuy scheme keep changing as the proposal works its way through the Oireachtas to become law. Photograph: Dominic Lipinski/PA Wire

I’m getting a loan of 72% of the house price. Do I qualify for a grant under the scheme?

Taking on the role of landlord when renting out your apartment can be a 24/7 responsibility and  does not suit everyone. Photograph: Brenda Fitzsimons / THE IRISH TIMES

People invariably underestimate the costs involved in maintaining a rental property

Pensioners protest outside Government Buildings last year. By 2055,  just two people are estimated will be working for every person in retirement, compared to about five today. Photograph: Dara Mac Dónaill/The Irish Times

Report urges introduction of mandatory savings to reduce pressure on State pension

Caroline Spillane, director general of Engineers Ireland

Survey of members of Engineers Ireland working in Ireland or Britain reveals that 40 per cent have had commercial deals deferred o(...)

Revenue will not be handling any applications for rebates under the first-time buyer help-to-buy scheme until January 1st. Photograph: Joe St Leger

Rules for first-time buyer rebate differ depending on a range of circumstances

 Industry sources say the State  lost between €4 million and €5 million by the delay in reducing the price of Pfizer’s  blockbuster arthritis drug  Enbrel. Photograph: Paul Faith/AFP/Getty Images

Even with 30% cut in Pfizer’s blockbuster Enbrel, Biogen’s Benepali delivers extra savings for health budget

Nuritas chief executive Emmet Browne said diabetes prevention was the first important area of focus for the company, though it expects to target other conditions in future

Company founded by Trinity mathematician secures €3m from EU to fund trials in Ireland

Dublin TDs and property interests are to the fore of lobbying for amendments to the Finance Bill in relation to the help-to-buy scheme, citing unfair advantage for rural dwellers.

Intensive lobbying is taking place in relation to possible amendment to Finance Bill

Pfizer’s  Enbrel lost patent protection in Europe earlier this year. Biogen introduced Benepali into the Irish market in September

Price drop is first under pricing deal signed by Government and Irish Pharmaceutical Healthcare Association

Buying a house: just because the minimum requirement is 70 per cent does not mean you must borrow only 70 per cent. Photograph: Paul Faith/PA Wire

Q&A: Dominic Coyle answers your personal finance questions

A Revenue spokeswoman said the delay was in advance of “a greater clampdown on offshore assets next year”. File photograph: iStock

People with offshore income and assets warned to settle outstanding liabilities

Minister for Finance Michael Noonan has moved to close off a loophole that allowed holders of certain pensions avoid tax. Photograph: Alan Betson

Holders could avail of tax relief but pay no tax on funds that were then passed on to next generation

 Minister for Finance Michael Noonan: Tax evaders have been given six months to get their affairs in order in relation to offshore assets under the Finance Bill. The measure is likely to lead to a cash windfall for the Revenue between now and the end of April next year. Photograph: Barbara Lindberg

Revenue in line for windfall as Finance Bill sets May 1st deadline for putting affairs in order

Even with a maximum rebate, a couple buying a €400,000 home will need to find €38,000 for their deposit. Photograph: Peter Byrne/PA Wire

Threshold for first-time-buyer scheme reduced to 70 per cent of property’s value

Where a generic medicine is a cheaper identical “copy” of a branded traditional small molecule drug, biosimilar are “me-too” versions of modern, large molecule complex biologic medicines

Drug manufacturers’ lobby group Ipha urges caution over study of competing treatments

There had been fears that close to 200 jobs at the EMC Cork plant could be at risk but staff say the number is now likely to be closer to a quarter of that figure.

Job losses expected to number about 50 as business is merged with Dell after takeover

Mel Gibson  on the set of his latest movie, The Professor and the Madman, which he is shooting in Dublin city and Ardmore with Sean Penn

Bray studios put on the market following three highly successful years financially

How much of a rebate you can claim in any one year will likely be set down in the Finance Bill

Precise detail of Help-to-Buy rebate scheme will not be clear until the Finance Bill is passed

Liberties Press faced bills of €267,802 over the 12 months to the end of July 2016. Photograph: iStockPhoto

It has made efforts to cut costs but has seen an increase in money debtors owes to it

The Joe Duffy group has 14 dealerships across the State representing 15 brands

Motor retailer says its financial performance was ‘extremely encouraging’

Jayne Brady, partner at Kernel with  Bob Pollard, chief executive of  Causeway Sensors, a spin-off company from Queen’s University Belfast  set up by   Pollard –  along with  Robert Bowman and John Nelson –  which has developed nano-sized sensing chips   used to detect early-stage cancer

Belfast-based Causeway Sensors makes nano-sized chips used to detect diseases

When can I have one? The help-to-buy rebate scheme applies to homes bought since July 19th, 2016, but Revenue will not start processing applications until January 1st, 2017. Photograph: Brian Lawless/PA Wire

Mortgage relief of up to €20,000 will be available to owner occupiers in new builds

“There is nothing to stop either or both parents gifting up to €3,000 to each child in any calendar year.” Photograph: Alan Betson/The Irish Times

Q&A: Dominic Coyle answers your personal finance questions

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