US hospital warns 179 patients may have been exposed to superbug

Drug-resistant bug may have contributed to deaths at Los Angeles centre

A large Los Angeles public hospital has notified scores of patients that they were possibly exposed to a drug-resistant “superbug” during endoscopy procedures that infected seven patients and may have contributed to two deaths.

The 179 patients who may have been infected by carbapenem-resistant Enterobacteriaceae (CRE) are being offered home-testing kits that would be analysed by the University of California, Los Angeles (UCLA) hospital system, UCLA officials said.

The possible exposures occurred at the UCLA Ronald Reagan Medical Center between October and January during procedures in which a specialised endoscope is inserted down the throat to diagnose and treat pancreatic and bile duct diseases.

Exposures

Hospitals across the United States have reported exposures from the same type of medical equipment in recent years, and the US Food and Drug Administration (FDA) has said it was working with other government agencies and manufacturers of the scopes to minimise risks.

READ MORE

The hospital said it had been sterilising the scopes according to the manufacturer’s standards, but was now using a more rigorous process.

“The two scopes involved with the infection were immediately removed, and UCLA is now utilising a decontamination process that goes above a and beyond manufacturer and national standards,” the hospital said in a statement.

UCLA spokeswoman Roxanne Moster said both scopes in question, which the hospital started using in June 2014, have been set aside permanently and will be returned to the manufacturer.

The condition and prognosis of the seven patients known to have been infected at Ronald Reagan Medical Center was not disclosed, nor were the circumstances of the two deaths in which CRE infection may have been a contributing factor. Both the Los Angeles and California health departments were notified as soon as the bacteria were detected, the hospital said.

Superbug infections are difficult to treat because some of the bacteria have become resistant to antibiotics, and the US Centers for Disease Control and Prevention said the germs could contribute to death in up to 50 per cent of infected patients.

The complex design of the endoscopes linked to the California outbreak, known as duodenoscopes, may hinder proper cleaning, the FDA warns. The FDA said it wanted to raise awareness among health professionals that the design is associated with a risk of resistant infections even when cleaning instructions are followed correctly. – (Reuters)